Hewes R C, Vigorita V J, Freiberger R H
Radiology. 1983 Jul;148(1):69-72. doi: 10.1148/radiology.148.1.6856867.
The diagnostic value of the microscopic examination of bone core specimen versus osseous blood, obtained by 110 percutaneous biopsies performed on 100 patients, was evaluated. A diagnosis of malignancy was made by biopsy in 54 cases. In 52 cases in which osseous blood (clot and smears) was available for examination, a positive diagnosis for malignancy was made microscopically in 49 (94%). In 46 cases in which bone cores were studied separately, a microscopic diagnosis of malignancy was made from the bone core in 39 (85%). If osseous blood had not been available for examination only 39 (72%) of the 54 biopsies would have been positive for malignancy; the other 14 biopsies would have been classified as either negative or insufficient for diagnosis. In those biopsies where both bone cores and osseous blood were available, the osseous blood showed better malignant tissue morphology and was considered better diagnostic material in 19 cases, whereas bone cores were considered better diagnostic material in only three cases. Osseous blood, which is usually easily available in bone biopsies, is valuable diagnostic material; it should be treated as a tissue specimen and not discarded.
对100例患者进行的110次经皮活检所获取的骨芯标本与骨血的显微镜检查的诊断价值进行了评估。54例经活检确诊为恶性肿瘤。在52例可获得骨血（凝块和涂片）进行检查的病例中，显微镜下确诊为恶性肿瘤的有49例（94%）。在46例单独研究骨芯的病例中，从骨芯中显微镜诊断为恶性肿瘤的有39例（85%）。如果无法获得骨血进行检查，54例活检中只有39例（72%）会呈恶性肿瘤阳性；其他14例活检将被归类为阴性或诊断不足。在那些同时有骨芯和骨血的活检中，骨血显示出更好的恶性组织形态，19例被认为是更好的诊断材料，而只有3例认为骨芯是更好的诊断材料。骨血在骨活检中通常很容易获得，是有价值的诊断材料；应将其视为组织标本而不应丢弃。
