Davison T F, Rowell J G, Rea J
Res Vet Sci. 1983 Mar;34(2):236-9.
Four-week-old chickens were fed on diets containing 0, 5, 10, 20 and 40 mg corticosterone per kg for eight days. Packed cell volume (PCV), the numbers of granulocytes (G) and lymphocytes (L), the G:L ratio and plasma corticosterone concentration were measured. Plasma corticosterone concentration was increased by dietary corticosterone from day 2 onwards. The number of lymphocytes was increased by serial bleeding but dietary corticosterone depressed the response and caused a dose-related lymphocytopenia from day 1. There was a dose related increase in granulocytes from day 4 and a dose-related increase in G:L ratio from day 1. A dose-related increase in PCV was evident only on days 2 and 4. Correlation coefficients showed little evidence of relationships between plasma corticosterone concentrations and the recorded blood variables.
给四周龄的小鸡喂食每千克分别含0、5、10、20和40毫克皮质酮的日粮，持续八天。测量红细胞压积（PCV）、粒细胞（G）和淋巴细胞（L）的数量、G:L比值以及血浆皮质酮浓度。从第2天起，日粮中的皮质酮使血浆皮质酮浓度升高。连续放血使淋巴细胞数量增加，但日粮中的皮质酮抑制了这种反应，并从第1天起导致剂量相关的淋巴细胞减少。从第4天起，粒细胞数量呈剂量相关增加，从第1天起，G:L比值呈剂量相关增加。仅在第2天和第4天，PCV呈剂量相关增加。相关系数显示，血浆皮质酮浓度与记录的血液变量之间几乎没有关系。
