Roux H, Gaborit P, Bonnefoy-Cudraz M, Deslous-Paoli M P, Fouquet B, Nowakovitch G
Rev Rhum Mal Osteoartic. 1983 Feb;50(2):105-9.
The authors present six cases of rheumatoid arthritis (RA) complicated by vasculitis of varying clinical presentation: 2 cases of polyneuritis, 5 cases of skin lesions (dry gangrene, ulcers, purpura). The severity of the clinical picture required, in addition to the usual treatment (corticosteroids, immunosuppressants), plasma exchanges. A clinical stabilisation was obtained in every case with good tolerance. The development of a vasculitis would appear to be the prime indication for the use of plasma exchange in rheumatoid arthritis.
作者报告了6例类风湿关节炎(RA)合并血管炎的病例,临床表现各异:2例为多发性神经炎,5例为皮肤病变(干性坏疽、溃疡、紫癜)。除常规治疗(皮质类固醇、免疫抑制剂)外,临床症状的严重程度还需要进行血浆置换。所有病例均获得临床稳定,耐受性良好。血管炎的发生似乎是类风湿关节炎中使用血浆置换的主要指征。