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[家族性复发性甲状旁腺功能亢进症。关于同一家族3名成员中的7例腺瘤。文献综述]

[Familial and recurrent hyperparathyroidism. Apropos of 7 adenomas in 3 members of the same family. Review of the literature].

作者信息

Doury P, Eulry F, Pattin S, Fromantin M, Gautier D, Bernard J, Tabaraud F, Masson C, Dano P

出版信息

Rev Rhum Mal Osteoartic. 1983 Feb;50(2):99-103.

PMID:6857134
Abstract

Over a period of 23 years, 3 members of a family of 5 presented with 7 parathyroid adenomas (4 in the first case, 2 in the second case, 1 in the third case). Excision of each adenoma, with systematic pre-operative assessment of the remaining parathyroid tissue, led to complete clinical and laboratory cure of each episode. The delay in the appearance of recurrence was between 3 and 9 years. After reviewing the literature, the authors stress the importance, in any case of hyperparathyroidism, of routinely investigating the serum calcium levels in members of the patient's family, especially if the patient is young and if he has had several episodes or a multiglandular involvement in the one episode. The authors discuss the literature concerning recurrent familial hyperparathyroidism with endocrine polyadenomatosis and the "hypercalcaemia - hypocalciuria" syndrome.

摘要

在23年的时间里,一个五口之家的3名成员出现了7例甲状旁腺腺瘤(第一例4个,第二例2个,第三例1个)。对每个腺瘤进行切除,并对剩余甲状旁腺组织进行系统的术前评估,使每一次发作都在临床和实验室检查上完全治愈。复发出现的延迟时间为3至9年。在回顾文献后,作者强调,在任何甲状旁腺功能亢进的病例中,常规检查患者家庭成员的血清钙水平都很重要,特别是当患者年轻且有多次发作或在一次发作中出现多腺体受累时。作者讨论了有关复发性家族性甲状旁腺功能亢进伴内分泌性多腺瘤病和“高钙血症 - 低钙尿症”综合征的文献。

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