Forsberg S A
Acta Med Scand. 1978;204(1-2):11-5. doi: 10.1111/j.0954-6820.1978.tb08390.x.
A total of 140 patients given permanent pacemaker 1963--73 were followed during three years with regard to survival. Indication of pacemaker implantation was AV block in 82% and disturbed consciousness in 84%. The first half of the series had a survival equal to that of the second half. The survival was 86, 73 and 64% and the excess mortality, which is above normal, was 9, 16 and 20% after one, two and three years, respectively. Concepts of fractional life-time and death-time were developed. These express the proportion of the total observation time that is life and death, respectively. The fractional life-time was 0.80 and the fractional death-time 0.20. The excess death-time was 0.12 (12%) of the total observation time. Mortality, survival, life-time and death-time were compared in three studies, the present one and two from Denmark. The great similarities were obvious. An estimation of the unpaced survival during three years, based on studies of AV block before the pacemaker era, indicated the great benefit of pacemaker treatment.
1963年至1973年间接受永久性起搏器植入的140名患者在三年期间接受了生存情况随访。起搏器植入的指征为82%的房室传导阻滞和84%的意识障碍。该系列的前半部分生存率与后半部分相当。一年、两年和三年后的生存率分别为86%、73%和64%,高于正常水平的额外死亡率分别为9%、16%和20%。提出了部分生存期和死亡期的概念。这些分别表示总观察时间中生存和死亡所占的比例。部分生存期为0.80,部分死亡期为0.20。额外死亡期占总观察时间的0.12(12%)。在本研究以及丹麦的两项研究中对死亡率、生存率、生存期和死亡期进行了比较。明显存在很大的相似性。基于起搏器时代之前对房室传导阻滞的研究,对三年未起搏生存情况的估计表明了起搏器治疗的巨大益处。