Weber H
Spine (Phila Pa 1976). 1983 Mar;8(2):131-40.
Two hundred eighty patients with herniated lumbar discs, verified by radiculography, were divided into three groups. One group, which mainly will be dealt with in this paper, consisted of 126 patients with uncertain indication for surgical treatment, who had their therapy decided by randomization which permitted comparison between the results of surgical and conservative treatment. Another group comprising 67 patients had symptoms and signs that beyond doubt, required surgical therapy. The third group of 87 patients was treated conservatively because there was no indication for operative intervention. Follow-up examinations in the first group were performed after one, four, and ten years. The controlled trial showed a statistically significant better result in the surgically treated group at the one-year follow-up examination. After four years the operated patients still showed better results, but the difference was no longer statistically significant. Only minor changes took place during the last six years of observation.
经神经根造影证实的280例腰椎间盘突出症患者被分为三组。本文主要讨论的一组由126例手术治疗指征不明确的患者组成，他们通过随机化决定治疗方式，从而能够比较手术治疗和保守治疗的结果。另一组67例患者有明确无疑需要手术治疗的症状和体征。第三组87例患者因无手术干预指征而接受保守治疗。第一组在1年、4年和10年后进行随访检查。对照试验显示，在1年的随访检查中，手术治疗组的结果在统计学上有显著更好的表现。4年后，接受手术的患者仍有较好的结果，但差异不再具有统计学意义。在最后6年的观察期内仅发生了微小变化。
