Tenchova V B, Pantev T P, Minkova M I
Strahlentherapie. 1983 Apr;159(4):248-50.
The kinetics of the changes of the nucleic acids level in the leucocytes of mice, as well as the leucocyte count were traced over a 30 day period, after a 2 Gy gamma irradiation. The changes of these parameters, which are dose-bound, were examined at the 24th and 72nd hour after irradiation with doses, belonging to the 0,1 to 6,0 Gy dose range. During the progress of the radiation damage the changes in the nucleic acids show a phase character that reaches its minimum on day 3 postradiation, with a recovery about day 30. The relation nucleic acids level/radiation dose is described with a logarithmic function. With both time intervals the nucleic acids level decreases with the logarithm of the dose, the reduction in the nucleic acids concentration being more clearly marked on day 3 postradiation. The rate of the nucleic acids level change is not adequate to that of the leucocyte count.
在2 Gy伽马射线照射后，对小鼠白细胞中核酸水平的变化动力学以及白细胞计数进行了为期30天的追踪。在照射后第24小时和72小时，检查了这些与剂量相关的参数变化，剂量范围为0.1至6.0 Gy。在辐射损伤进展过程中，核酸变化呈现阶段性特征，在辐射后第3天达到最小值，约在第30天恢复。核酸水平/辐射剂量的关系用对数函数描述。在两个时间间隔内，核酸水平均随剂量的对数下降，辐射后第3天核酸浓度的降低更为明显。核酸水平变化速率与白细胞计数的变化速率不相符。
