Drăgănescu N, Antipa C, Gîrjabu E, Melencu M
Virologie. 1983 Jan-Mar;34(1):3-6.
Serum samples from patients with endemic Balkan nephropathy (EBN) were inoculated intraperitoneally to four species of laboratory animals. It was only in the guinea pig that a serially transmissible experimental disease occurred, after a long incubation period. The morphopathological features in the guinea pig were similar to those encountered in the terminal phase of human EBN. The hypothesis that EBN might be a slow virus disease is discussed.
将来自地方性巴尔干肾病(EBN)患者的血清样本腹腔内接种到四种实验动物身上。只有在豚鼠身上,经过很长的潜伏期后出现了一种可连续传播的实验性疾病。豚鼠的形态病理学特征与人类EBN终末期的特征相似。文中讨论了EBN可能是一种慢病毒疾病的假说。