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[第三脑室肿瘤,临床方面与治疗]

[Tumors of the 3d ventricle, clinical aspects and treatment].

作者信息

Russegger L, Kostron H, Grunert V, Pallua A

出版信息

Zentralbl Neurochir. 1983;44(1):73-82.

PMID:6858464
Abstract

Our last 30 patients, who were operated upon 3rd-ventricle-tumors, are discussed on symptomatology, diagnosis and therapy. Depending on the localization we classify oral, basal and caudal tumors. The peak of these tumors is found in the first ten years of life. They are distributed as followed: spongioblastomas, ependymomas, pinealoma and other rare tumors. Mainsymptom is the sudden diffuse headache depending on this skull's position. The three groups show different symptomatic features, the oral one sepecially that headache described above. The symptoms of the caudal group are due to signs of raised intracranial pressure and content the typical syndrome of the lamina-quadrigemina. Basal tumors lead to diencephalic disturbances. The CT scan should be done as the first diagnostic step, eventually connected with ventriculography or ventriculotomography. In any case therapy should be started by implantation of an atrio-ventriculare shunt. If the disease is progressing an invasive procedure has to be done. Irradiation therapy is bound to a clear histologic diagnosis or to a clear inoperability. Our 5-years survival was 40% in average.

摘要

我们对最近接受第三脑室肿瘤手术的30例患者的症状学、诊断和治疗进行了讨论。根据肿瘤的位置,我们将其分为口部、底部和尾部肿瘤。这些肿瘤的发病高峰出现在生命的前十年。其分布如下:成胶质细胞瘤、室管膜瘤、松果体瘤和其他罕见肿瘤。主要症状是根据颅骨位置出现的突发性弥漫性头痛。这三组表现出不同的症状特征,口部肿瘤组尤其有上述头痛症状。尾部肿瘤组的症状是由于颅内压升高的体征,包括典型的四叠体板综合征。底部肿瘤会导致间脑功能障碍。CT扫描应作为首要诊断步骤,最终可结合脑室造影或脑室断层扫描。无论如何,治疗应首先植入房室分流管。如果病情进展,则必须进行侵入性手术。放射治疗必须基于明确的组织学诊断或明确的不可手术性。我们的患者平均5年生存率为40%。

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