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脊髓性肌萎缩症中的手部和心电图震颤。

Hand and ECG tremor in spinal muscular atrophy.

作者信息

Dawood A A, Moosa A

出版信息

Arch Dis Child. 1983 May;58(5):376-8. doi: 10.1136/adc.58.5.376.

DOI:10.1136/adc.58.5.376
PMID:6859919
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1627871/
Abstract

The presence of hand and electrocardiogram (ECG) tremor was studied in 31 children with severe, intermediate, or mild form of spinal muscular atrophy. Clinical tremor of the hands was seen in 16 (59%) of 27 patients, all with benign forms of the disease. Nineteen patients had ECG tremors, of whom 17 had the mild or intermediate form. With the exception of one, all patients in the mild or intermediate group had hand or ECG tremor. Hand and ECG tremor are valuable in the diagnosis of the benign forms of spinal muscular atrophy; they are of no value in diagnosis of the severe infantile type.

摘要

对31例患有重度、中度或轻度脊髓性肌萎缩症的儿童进行了手部震颤和心电图(ECG)震颤的研究。27例患者中有16例(59%)出现手部临床震颤,均为病情良性的患者。19例患者有心电图震颤,其中17例为轻度或中度。除1例患者外,轻度或中度组的所有患者均有手部或心电图震颤。手部震颤和心电图震颤对脊髓性肌萎缩症良性形式的诊断有价值;对重度婴儿型的诊断无价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbd4/1627871/dc97d78515db/archdisch00746-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbd4/1627871/dc97d78515db/archdisch00746-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbd4/1627871/dc97d78515db/archdisch00746-0065-a.jpg

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本文引用的文献

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INFANTILE MUSCULAR ATROPHY. A PROSPECTIVE STUDY WITH PARTICULAR REFERENCE TO A SLOWLY PROGRESSIVE VARIETY.婴儿型肌肉萎缩症。一项前瞻性研究,特别关注一种缓慢进展型。
Brain. 1964 Dec;87:707-18. doi: 10.1093/brain/87.4.707.
2
Is Kugelberg-Welander spinal muscular atrophy a fetal defect?库格勒贝格-韦兰德型脊髓性肌萎缩症是一种胎儿缺陷吗?
Muscle Nerve. 1980 Sep-Oct;3(5):389-402. doi: 10.1002/mus.880030503.
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Neurogenic muscular atrophy of infancy with prolonged survival. The variable course of Werdnig-Hoffmann Disease.婴儿期神经源性肌肉萎缩伴生存期延长。韦尔尼克-霍夫曼病的可变病程。
全员出动:神经肌肉疾病患者手部功能的多学科康复评估与管理
Muscle Nerve. 2025 May;71(5):869-888. doi: 10.1002/mus.28167. Epub 2024 Jun 6.
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Drug Discovery of Spinal Muscular Atrophy (SMA) from the Computational Perspective: A Comprehensive Review.从计算角度看脊髓性肌萎缩症(SMA)的药物发现:全面综述。
Int J Mol Sci. 2021 Aug 20;22(16):8962. doi: 10.3390/ijms22168962.
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Magnetic resonance imaging of the cervical spinal cord in spinal muscular atrophy.脊髓性肌萎缩症的颈椎磁共振成像。
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Trembling hands and trembling ECG.双手颤抖与心电图震颤。
BMJ Case Rep. 2019 Jun 2;12(6):e230618. doi: 10.1136/bcr-2019-230618.
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