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婴儿期唾液皮质醇值昼夜节律出现的年龄。

Age of appearance of circadian rhythm in salivary cortisol values in infancy.

作者信息

Price D A, Close G C, Fielding B A

出版信息

Arch Dis Child. 1983 Jun;58(6):454-6. doi: 10.1136/adc.58.6.454.

DOI:10.1136/adc.58.6.454
PMID:6859940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1628010/
Abstract

Samples of saliva (4 in 24 hours), collected at monthly intervals for the first 6 months of life in 8 term infants by their mothers, were analysed for cortisol by radioimmunoassay. Values in the first month were more variable, daily mean values were greater, and amplitudes of variation were greater than in subsequent months. The circadian rhythm appeared by the third month.

摘要

8名足月儿的母亲在其出生后头6个月每月采集一次唾液样本（24小时内采集4次），通过放射免疫分析法检测皮质醇。第一个月的值变化更大，日均值更高，且变化幅度大于随后几个月。昼夜节律在第三个月出现。

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本文引用的文献

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Use of saliva for monitoring unbound free cortisol levels in serum.利用唾液监测血清中未结合的游离皮质醇水平。
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Diurnal variation of plasma 17-hydroxycorticosteroids in children.儿童血浆17-羟皮质类固醇的昼夜变化
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A method for obtaining saliva samples from infants and young children.一种从婴幼儿获取唾液样本的方法。
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