Piccardo M G, Russo L, Rosa M
Boll Soc Ital Biol Sper. 1983 Jan 31;59(2):161-6.
The dopaminergic agonist Bromocriptine has been perfused in vivo in normal Wistar rats to control its activity on Glucose-3-H3 metabolism. Bromocriptine shows a rapid influence on glucose production rate (Ra) and glucose utilization rate (Rd). Both rates increase, but since Bromocriptine effects on glucose production rate is more significant than the ones on glucose utilization, the final results is an increase in plasma glucose levels. Since glucose production rate in normal animals is practically equal to hepatic glucose output, the most logical explantation of Bromocriptine activity is the activation of glycogenosis with a rise of plasma glucose levels.
多巴胺能激动剂溴隐亭已在正常Wistar大鼠体内进行灌注，以控制其对葡萄糖-3-H3代谢的活性。溴隐亭对葡萄糖生成率（Ra）和葡萄糖利用率（Rd）有快速影响。这两个速率均增加，但由于溴隐亭对葡萄糖生成率的影响比对葡萄糖利用率的影响更显著，最终结果是血浆葡萄糖水平升高。由于正常动物的葡萄糖生成率实际上等于肝脏葡萄糖输出量，对溴隐亭活性最合理的解释是糖原生成的激活以及血浆葡萄糖水平的升高。
