Carter R, Krantz K E, Hara G S, Lin F, Masterson B J, Smith S J
Am J Obstet Gynecol. 1978 Aug 15;131(8):831-6. doi: 10.1016/s0002-9378(16)33126-x.
Forty-five patients with histologically proved cervical dysplasia or carcinoma in situ were treated by the carbon dioxide-laser method. The carbon dioxide laser induces cell vaporization by causing intracellular steam combustion stimulated by the emission of a mixture of carbon dioxide, nitrogen, and helium. This method of treatment is easily performed in the outpatient clinic without anesthesia, is inexpensive, and is effective in the treatment of cervical intraepithelial neoplasia. The treatment allows preservation of the transformation zone, thus permitting future colposcopic visualization.