Steele R J, Blackie R A, McGregor J D, Forrest A P
Br J Surg. 1983 Jun;70(6):317-8. doi: 10.1002/bjs.1800700604.
The reactive changes in the axillary lymph nodes of 50 breast cancer patients treated by mastectomy immediately following frozen section diagnosis have been compared with the changes in the nodes of 50 patients whose biopsy preceded mastectomy by between 2 and 5 days. The frequency of sinus histiocytosis was significantly greater in those patients who had been subjected to previous biopsy. This finding suggests that prior breast biopsy may negate the prognostic significance of sinus histiocytosis in breast cancer.
对50例在冰冻切片诊断后立即行乳房切除术的乳腺癌患者腋窝淋巴结的反应性变化，与50例活检在乳房切除术前行2至5天的患者淋巴结变化进行了比较。先前接受过活检的患者中窦组织细胞增生的频率明显更高。这一发现表明，先前的乳房活检可能会使窦组织细胞增生在乳腺癌中的预后意义失效。
