Richards B, Newling D, Fossa S, Bastable J R, Denis L, Jones W B, de Pauw M
Cancer Treat Rep. 1983 Jun;67(6):575-7.
Thirty-seven patients with measurable deposits or primary lesions arising from transitional cell carcinoma of the bladder were treated with 1 mg/m2/week of vincristine. One complete response lasting 7 months was seen among the 23 patients with metastatic disease. Two partial responses were seen among the 14 patients with persistent primary tumor. Vincristine is not recommended for further evaluation as a single agent in transitional cell carcinoma of the bladder.
37例患有可测量的膀胱移行细胞癌沉积物或原发性病变的患者接受了每周1 mg/m²的长春新碱治疗。在23例转移性疾病患者中观察到1例持续7个月的完全缓解。在14例持续性原发性肿瘤患者中观察到2例部分缓解。不建议将长春新碱作为单一药物进一步评估用于膀胱移行细胞癌。
