曼氏血吸虫和/或埃及血吸虫单一或混合感染患者的IgG和IgE循环免疫复合物、血清总IgE及寄生虫相关IgE。治疗的影响。
IgG and IgE circulating immune complexes, total serum IgE and parasite related IgE in patients with mono- or mixed infection with Schistosoma mansoni and/or S. haematobium. Influence of therapy.
作者信息
Stevens W J, Feldmeir H, Bridts C H, Daffalla A A
出版信息
Clin Exp Immunol. 1983 Apr;52(1):144-52.
IgG and IgE containing circulating immune complexes (CIC), total serum IgE and parasite related IgE were determined in monoinfected patients with Schistosoma mansoni or S.haematobium and in patients with a mixed infection. IgE- and IgG-CIC and total serum IgE were significantly higher in the mixed infection group. There is considerable cross-reactivity between the crude S.haematobium and S.mansoni antigen preparations. The level of IgE-CIC is correlated to the levels of total serum IgE and parasite related IgE respectively. Furthermore IgE-CIC levels were related to the intensity of infection. Twelve out of 21 patients suffering from a monoinfection were reinvestigated 1-4 months after specific chemotherapy. Parasitological cure is followed by a significant decrease of total serum IgE and IgE-CIC, whereas parasite related IgE did not change significantly. The importance of the disappearance of IgE-CIC is discussed.
在单纯感染曼氏血吸虫或埃及血吸虫的患者以及混合感染患者中，检测了含有循环免疫复合物（CIC）的IgG和IgE、血清总IgE以及与寄生虫相关的IgE。混合感染组中IgE和IgG - CIC以及血清总IgE显著更高。埃及血吸虫和曼氏血吸虫的粗制抗原制剂之间存在相当程度的交叉反应性。IgE - CIC水平分别与血清总IgE水平和与寄生虫相关的IgE水平相关。此外，IgE - CIC水平与感染强度有关。21例单纯感染患者中有12例在特异性化疗后1 - 4个月接受了再次检查。寄生虫学治愈后，血清总IgE和IgE - CIC显著下降，而与寄生虫相关的IgE没有显著变化。文中讨论了IgE - CIC消失的重要性。
Zotero 插件