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人肾小球上的C3b受体体外研究。培养中的丧失。

C3b receptors on human glomeruli in vitro. Loss in culture.

作者信息

Scheinman J I, Fish A J, Kim Y, Michael A F

出版信息

Am J Pathol. 1978 Jul;92(1):147-54.

PMID:686145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2018587/
Abstract

C3b receptors, easily demonstrated on isolated human infant glomeruli, are lost as cells grow in culture. This suggests that epithelial cells are dedifferentiated or that the C3b receptor is not intrinsic to the epithelial cell.

摘要

C3b受体在分离出的人类婴儿肾小球上很容易被证实，但随着细胞在培养中生长，这些受体会消失。这表明上皮细胞去分化了，或者C3b受体并非上皮细胞所固有。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e9/2018587/e2f1d7d657b1/amjpathol00735-0162-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e9/2018587/c15d8982334f/amjpathol00735-0163-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e9/2018587/e6350ef005aa/amjpathol00735-0163-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e9/2018587/b2d98dcf4863/amjpathol00735-0162-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e9/2018587/e2f1d7d657b1/amjpathol00735-0162-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e9/2018587/c15d8982334f/amjpathol00735-0163-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e9/2018587/e6350ef005aa/amjpathol00735-0163-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e9/2018587/b2d98dcf4863/amjpathol00735-0162-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e9/2018587/e2f1d7d657b1/amjpathol00735-0162-b.jpg

相似文献

1
C3b receptors on human glomeruli in vitro. Loss in culture.人肾小球上的C3b受体体外研究。培养中的丧失。
Am J Pathol. 1978 Jul;92(1):147-54.
2
Immune adherence in renal glomeruli. Complement receptor sites on glomerular capillary epithelial cells.肾小球中的免疫黏附。肾小球毛细血管上皮细胞上的补体受体位点。
Am J Pathol. 1977 Mar;86(3):635-54.
3
Localization of receptors for activated complement on visceral epithelial cells of the human renal glomerulus.活化补体受体在人肾小球脏层上皮细胞上的定位。
J Immunol. 1977 Mar;118(3):869-73.
4
Characterization of the human glomerular C3 receptor as the C3b/C4b complement type one (CR1) receptor.人肾小球C3受体作为C3b/C4b补体1型（CR1）受体的特性
J Immunol. 1986 Feb 15;136(4):1373-7.
5
Isolation of phagocytic cells from the rat renal glomerulus.从大鼠肾小球中分离吞噬细胞。
Lab Invest. 1976 Oct;35(4):315-26.
6
Rat glomerular cells do not express podocytic markers when cultured in vitro.大鼠肾小球细胞在体外培养时不表达足细胞标志物。
Lab Invest. 1991 Nov;65(5):548-57.
7
Polygonal epithelial cells in glomerular cell culture: Podocyte or parietal epithelial origin?肾小球细胞培养中的多边形上皮细胞：足细胞还是壁层上皮来源？
Microsc Res Tech. 2002 May 15;57(4):212-6. doi: 10.1002/jemt.10075.
8
Human complement (C3b) receptors defined by a mouse monoclonal antibody.由小鼠单克隆抗体界定的人补体（C3b）受体。
Immunology. 1982 Apr;45(4):645-53.
9
The effect of complement in adherent immune complexes on Fc and C3 receptor expression in human monocytes.黏附性免疫复合物中的补体对人单核细胞Fc和C3受体表达的影响。
Immunology. 1981 Dec;44(4):717-25.
10
Differentiation of C3b receptors on human lymphocytes, phagocytes, erythrocytes and renal glomerulus cells by monoclonal antibodies.用单克隆抗体对人淋巴细胞、吞噬细胞、红细胞和肾小球细胞上C3b受体的鉴别
Immunology. 1982 Jan;45(1):85-96.

引用本文的文献

1
Metanephric development in serum-free organ culture.无血清器官培养中的后肾发育
In Vitro. 1982 Aug;18(8):675-82. doi: 10.1007/BF02796422.
2
The growth of primary glomerular cells as a confluent monolayer in a chemically defined serum-free medium: specific requirements for prostaglandins and extracellular matrix molecules.原代肾小球细胞在化学成分明确的无血清培养基中形成汇合单层的生长：对前列腺素和细胞外基质分子的特定需求。
Am J Pathol. 1981 Aug;104(2):181-8.
3
IgG Fc membrane receptor on normal human glomerular visceral epithelial cells.正常人肾小球脏层上皮细胞上的IgG Fc膜受体。

本文引用的文献

1
The glomerular complement receptor in immunologically mediated renal glomerular injury.免疫介导的肾小球损伤中的肾小球补体受体
N Engl J Med. 1976 Jul 1;295(1):10-4. doi: 10.1056/NEJM197607012950103.
2
A receptor for the third component of complement in the human renal glomerulus.人类肾小球中补体第三成分的一种受体。
J Exp Med. 1975 Oct 1;142(4):1029-34. doi: 10.1084/jem.142.4.1029.
3
Isolation of phagocytic cells from the rat renal glomerulus.从大鼠肾小球中分离吞噬细胞。
Virchows Arch A Pathol Anat Histopathol. 1984;404(2):139-58. doi: 10.1007/BF00704059.
4
Factors influencing immune complex localisation.影响免疫复合物定位的因素。
Rheumatol Int. 1984;4(3):95-109. doi: 10.1007/BF00541177.
5
Glomerular antigens in glomerulonephritis.肾小球肾炎中的肾小球抗原。
Springer Semin Immunopathol. 1982;5(3):221-49. doi: 10.1007/BF01892087.
6
Human foetal kidney explants in serum-free organ culture.无血清器官培养中的人胎儿肾外植体
Anat Embryol (Berl). 1987;176(1):105-14. doi: 10.1007/BF00309758.
7
Lymphohaemopoietic antigens of cultured human glomerular epithelial cells.培养的人肾小球上皮细胞的淋巴造血抗原。
Br J Exp Pathol. 1989 Feb;70(1):73-82.
8
The ontogenesis of Fc gamma receptors and complement receptors CR1 in human peripheral nerve.人外周神经中Fcγ受体和补体受体CR1的个体发生
Acta Neuropathol. 1990;80(1):35-40. doi: 10.1007/BF00294219.
9
Human glomerular cells in culture. Three subcultured cell types bearing glomerular antigens.培养中的人肾小球细胞。三种带有肾小球抗原的传代培养细胞类型。
Am J Pathol. 1978 Jul;92(1):125-46.
10
Culture of human glomerular cells.人肾小球细胞培养。
Am J Pathol. 1979 Jul;96(1):101-19.
Lab Invest. 1976 Oct;35(4):315-26.
4
Control of Fc and C3 receptors on myeloid leukemic cells.髓系白血病细胞上Fc和C3受体的调控
J Immunol. 1976 Aug;117(2):580-6.
5
Localization of receptors for activated complement on visceral epithelial cells of the human renal glomerulus.活化补体受体在人肾小球脏层上皮细胞上的定位。
J Immunol. 1977 Mar;118(3):869-73.
6
Immune adherence in renal glomeruli. Complement receptor sites on glomerular capillary epithelial cells.肾小球中的免疫黏附。肾小球毛细血管上皮细胞上的补体受体位点。
Am J Pathol. 1977 Mar;86(3):635-54.
7
Human glomerular smooth muscle (mesangial) cells in culture.培养中的人肾小球平滑肌（系膜）细胞。
Lab Invest. 1976 Feb;34(2):150-8.
8
Human glomerular cells in culture. Three subcultured cell types bearing glomerular antigens.培养中的人肾小球细胞。三种带有肾小球抗原的传代培养细胞类型。
Am J Pathol. 1978 Jul;92(1):125-46.
9
Diminished glomerular accumulation of colloidal carbon in autologous immune complex nephritis.自体免疫复合物性肾炎中胶体碳的肾小球蓄积减少。
Lab Invest. 1977 Jul;37(1):9-19.
10
The macrophagen in human rapidly progressive glomerulonephritis.人类急进性肾小球肾炎中的巨噬细胞。
Lancet. 1976 Apr 17;1(7964):830-2. doi: 10.1016/s0140-6736(76)90480-3.