Fenske N A, Waisman M, Espinoza C G
Cutis. 1983 Jun;31(6):673-7.
Bowen's disease is a squamous cell carcinoma characterized by isolated, grouped or confluent nodules, either flat, scaling, or crusted, with an arcuate or serpiginous configuration. Malignant dyskeratosis throughout the epidermis, the bowenoid hallmark, is not sufficient by itself to identify a lesion as Bowen's disease. It has been suggested, but not proven, that arsenic has a role in the etiology of Bowen's disease. A case of Bowen's disease affecting the palm, an unusual location, is reported.
鲍恩病是一种鳞状细胞癌,其特征为孤立、成簇或融合的结节,可为扁平、鳞屑状或结痂状,呈弧形或匐行状。表皮全层的恶性角化不良是鲍恩样特征,但仅凭此不足以将病变识别为鲍恩病。有人提出砷在鲍恩病的病因中起作用,但尚未得到证实。本文报告了一例发生于手掌(一个不寻常部位)的鲍恩病病例。