Firooz Alireza, Farsi Nader, Rashighi-Firoozabadi Mehdi, Gorouhi Farzam
Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran.
Arch Iran Med. 2007 Apr;10(2):255-7.
Pigmented Bowen's disease is an uncommon in situ squamous cell carcinoma of the skin, which has been rarely reported on the finger. Herein, we report an unusual case of pigmented Bowen's disease of the pulp of the fourth finger in a 20-year-old white woman, which was clinically presented as a superficial, spreading malignant melanoma. Physical examination revealed a solitary hyperpigmented patch, measuring 1 cm in its greatest diameter. The lesion had an irregular, but well-defined margin, and was homogeneously brown with a smooth surface. There was no nodularity or induration in the lesion or in its surrounding skin. A skin biopsy was obtained with the clinical suspicion of malignant melanoma. Histological examination was compatible with the diagnosis of pigmented Bowen's disease. Surgical treatment was then considered and the patient underwent complete excision of the lesion. In spite of its rarity, Bowen's disease should be considered in the differential diagnosis of pigmented lesions, particularly malignant melanoma.
色素沉着性鲍恩病是一种罕见的皮肤原位鳞状细胞癌，很少有关于手指部位的报道。在此，我们报告一例20岁白人女性右手环指指腹色素沉着性鲍恩病的罕见病例，该病例临床上表现为浅表播散性恶性黑色素瘤。体格检查发现一个孤立的色素沉着斑，最大直径为1厘米。病变边缘不规则但清晰，呈均匀褐色，表面光滑。病变及其周围皮肤无结节或硬结。因临床怀疑恶性黑色素瘤而进行了皮肤活检。组织学检查结果符合色素沉着性鲍恩病的诊断。随后考虑手术治疗，患者接受了病变的完整切除。尽管鲍恩病罕见，但在色素沉着性病变，尤其是恶性黑色素瘤的鉴别诊断中应考虑到该病。
