Royer R E, Vander Jagt D L
FEBS Lett. 1983 Jun 27;157(1):28-30. doi: 10.1016/0014-5793(83)81109-0.
The triterpene gossypol competes with bilirubin for a high-affinity binding site on human serum albumin. Similar competition between bilirubin and gossypol occurs in the binding of these ligands to the glutathione S-transferases from human liver and placenta. In each case, gossypol and bilirubin exhibit similar binding constants. The binding properties of gossypol may generally mimic those of bilirubin.
三萜类化合物棉酚与人血清白蛋白上的高亲和力结合位点竞争胆红素。胆红素与棉酚之间在这些配体与人肝脏和胎盘的谷胱甘肽S-转移酶的结合中也存在类似的竞争。在每种情况下，棉酚和胆红素都表现出相似的结合常数。棉酚的结合特性通常可能模拟胆红素的结合特性。
