Gutteridge J M
FEBS Lett. 1983 Jun 27;157(1):37-40. doi: 10.1016/0014-5793(83)81111-9.
The antioxidant activity of caeruloplasmin can be mainly ascribed to its ferroxidase activity which effectively inhibits ferrous ion-stimulated lipid peroxidation and ferrous ion-dependent formation of hydroxyl radicals in the Fenton reaction. In addition, caeruloplasmin can prevent copper ions from stimulating lipid peroxidation.
铜蓝蛋白的抗氧化活性主要归因于其亚铁氧化酶活性,该活性可有效抑制亚铁离子刺激的脂质过氧化反应以及芬顿反应中亚铁离子依赖的羟基自由基形成。此外,铜蓝蛋白还可防止铜离子刺激脂质过氧化。