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一种人类镭代谢的年龄依赖性模型。

An age dependent model for radium metabolism in man.

作者信息

Johnson J R

出版信息

Health Phys. 1983;44 Suppl 1:91-102. doi: 10.1097/00004032-198306001-00007.

Abstract

The model developed by a Task Group of Committee 2 of ICRP to describe Alkaline Earth Metabolism in Adult Man (ICRP Publication 20) has been modified so that recycling is handled explicitly, and retention in mineral bone is represented by second compartments rather than by the product of a power function and an exponential. This model has been extended to include all ages from birth to adult man, and has been coupled with modified "ICRP" lung and G.I. tract models so that activity in organs can be calculated as functions of time during or after exposures. These activities, and age dependent "specific effective energy" factors, are then used to calculate age dependent dose rates, and dose commitments. This presentation describes this work, with emphasis on the model parameters and results obtained for radium.

摘要

国际辐射防护委员会第2委员会一个特别工作组所开发的用于描述成年男性碱土金属代谢的模型(ICRP第20号出版物)已作修改,以便能明确处理再循环情况,并且矿物骨中的滞留情况由第二房室表示,而非由幂函数与指数函数的乘积表示。该模型已扩展到涵盖从出生到成年男性的所有年龄段,并且已与修改后的“ICRP”肺部和胃肠道模型相结合,从而能够将器官中的活度计算为照射期间或照射后时间的函数。然后,利用这些活度以及与年龄相关的“比有效能量”因子来计算与年龄相关的剂量率和剂量负担。本报告介绍了这项工作,重点是镭的模型参数和所得结果。

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