Llorens-Terol J, Martinez-Roig A
Helv Paediatr Acta. 1983 Mar;38(1):91-4.
Erythema nodosum is an immunoallergic epiphenomenon appearing during the course of various conditions; it has been exceptionally observed in association with infectious mononucleosis. A 9-year-old girl with clinical manifestations of infectious mononucleosis developed cutaneous nodules of erythema nodosum over the shins, which cleared after 12 days. Diagnosis was based on the presence of atypical mononuclear cells, detection of antibodies against Epstein-Barr virus, and positive ox red blood cell hemolysis. Coincidence of both diseases is not surprising because infectious mononucleosis may exhibit diverse immunologic reactions. On the other hand, commonest etiologies were excluded in this case.
结节性红斑是在各种疾病过程中出现的一种免疫过敏性附带现象；它曾罕见地与传染性单核细胞增多症相关联被观察到。一名患有传染性单核细胞增多症临床表现的9岁女孩在胫前出现了结节性红斑的皮肤结节，这些结节在12天后消退。诊断基于非典型单核细胞的存在、抗EB病毒抗体的检测以及阳性的羊红细胞溶血反应。两种疾病的巧合并不令人惊讶，因为传染性单核细胞增多症可能表现出多种免疫反应。另一方面，该病例排除了最常见的病因。
