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磁诱导热疗中的能量沉积模式:二维低频数值分析

Power deposition patterns in magnetically-induced hyperthermia: a two-dimensional low-frequency numerical analysis.

作者信息

Hill S C, Christensen D A, Durney C H

出版信息

Int J Radiat Oncol Biol Phys. 1983 Jun;9(6):893-904. doi: 10.1016/0360-3016(83)90016-0.

DOI:10.1016/0360-3016(83)90016-0
PMID:6863062
Abstract

The electric fields and power deposition patterns generated in two-dimensional inhomogenous models exposed to the axially directed uniform magnetic fields of an infinitely long solenoid are calculated numerically. The fields are calculated using the method of moments (Galerkin procedure) with linear basis and weighting functions. This low-frequency analysis is useful for studying the power deposition patterns attributable to solenoidal inductive applicators operated at frequencies up to 13.56 MHz. For the models we have studied, the ratio of power per volume deposited into the tumor to power per volume deposited into the immediately surrounding tissue is largest for tumors in the lung, although the power per volume deposited into the outermost layer is still much larger than the power per volume deposited into the tumor; it may be possible, however, to cool this region adequately from the body surface. When the complex permittivity of the tumor model is similar to that of the region in which it is embedded, the currents in the torso and tumor circulate primarily around the center of the body, as has been previously calculated for concentric cylinders. When the complex permittivity of the tumor is much greater than the region in which it is embedded, the currents in the tumor circulate primarily around the center of the tumor.

摘要

对暴露于无限长螺线管轴向均匀磁场中的二维非均匀模型所产生的电场和功率沉积模式进行了数值计算。使用具有线性基函数和加权函数的矩量法(伽辽金过程)来计算这些场。这种低频分析对于研究在高达13.56 MHz频率下运行的螺线管感应施加器所导致的功率沉积模式很有用。对于我们所研究的模型,尽管沉积到最外层的每体积功率仍远大于沉积到肿瘤中的每体积功率,但对于肺部肿瘤而言,沉积到肿瘤中的每体积功率与沉积到紧邻肿瘤周围组织中的每体积功率之比最大;然而,有可能从体表充分冷却该区域。当肿瘤模型的复介电常数与其所嵌入区域的复介电常数相似时,躯干和肿瘤中的电流主要围绕身体中心循环,这与之前对同心圆柱的计算结果一致。当肿瘤的复介电常数远大于其所嵌入区域的复介电常数时,肿瘤中的电流主要围绕肿瘤中心循环。

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