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热疗实验性癌症治疗中的“热图绘制”:半自动系统的描述与应用

"Thermal mapping" in experimental cancer treatment with hyperthermia: description and use of a semi-automatic system.

作者信息

Gibbs F A

出版信息

Int J Radiat Oncol Biol Phys. 1983 Jul;9(7):1057-63. doi: 10.1016/0360-3016(83)90397-8.

DOI:10.1016/0360-3016(83)90397-8
PMID:6863073
Abstract

The regions of tumor which are least adequately heated during experimental hyperthermia treatments will most likely determine the ultimate probability of tumor control. Temperature inhomogeneity during local or regional hyperthermia is often marked, and stationary temperature probes yield very little information about the adequacy or inadequacy of tumor heating. Fine catheters can be placed through the tumor bearing region and temperatures recorded at various points within these catheters, thus yielding valuable data about temperature variations within the volume of interest. The "thermal mapping system" (TMS) described herein provides a method for remotely sampling these temperature variations in a semi-automatic manner in several catheters simultaneously. Its application in conjunction with a commercial hyperthermia system is described and clinical examples of its use and importance are provided.

摘要

在实验性热疗治疗期间加热最不充分的肿瘤区域很可能决定肿瘤控制的最终概率。局部或区域热疗期间的温度不均匀性通常很明显,而固定温度探头提供的关于肿瘤加热是否充分的信息非常少。细导管可以穿过肿瘤所在区域放置,并记录这些导管内不同点的温度,从而得出有关感兴趣体积内温度变化的有价值数据。本文所述的“热图系统”(TMS)提供了一种以半自动方式同时对多个导管中的这些温度变化进行远程采样的方法。描述了其与商用热疗系统结合的应用,并提供了其使用和重要性的临床实例。

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"Thermal mapping" in experimental cancer treatment with hyperthermia: description and use of a semi-automatic system.热疗实验性癌症治疗中的“热图绘制”:半自动系统的描述与应用
Int J Radiat Oncol Biol Phys. 1983 Jul;9(7):1057-63. doi: 10.1016/0360-3016(83)90397-8.
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A physiological effect on tissue temperature during RF hyperthermia.射频热疗期间对组织温度的生理效应。
Br J Cancer. 1984 Jun;49(6):801-3. doi: 10.1038/bjc.1984.124.
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Improvement of local control by regional hyperthermia combined with systemic chemotherapy (ifosfamide plus etoposide) in advanced sarcomas: updated report on 65 patients.区域热疗联合全身化疗(异环磷酰胺加依托泊苷)改善晚期肉瘤局部控制:65例患者的最新报告
J Cancer Res Clin Oncol. 1991;117 Suppl 4:S141-7. doi: 10.1007/BF01613220.
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Hyperthermia in cancer therapy: where are we today and where are we going?癌症治疗中的热疗:我们如今处于何方,又将走向何处?
Bull N Y Acad Med. 1992 Mar-Apr;68(2):341-50.