Budd K
Anaesthesia. 1978 Jun;33(6):531-4. doi: 10.1111/j.1365-2044.1978.tb08391.x.
The psychotropic drugs in the treatment of chronic pain have value in several areas. They not only influence the mood of the patient but also provide hypnosis, augment the activity of the analgesics and exhibit analgesic potency in their own right. They may be used alone, or in combination with analgesic agents or with each other. The three most valuable groups are the antidepressants, tranquillizers and anticonvulsants, all of which exert their effect by influencing the intracerebral levels of various neurotransmitter amines.
治疗慢性疼痛的精神药物在几个方面具有价值。它们不仅会影响患者的情绪，还能起到催眠作用，增强镇痛药的活性，并且自身就具有镇痛效力。它们可以单独使用，或者与镇痛药联合使用，也可以相互联合使用。最具价值的三类药物是抗抑郁药、镇静剂和抗惊厥药，它们均通过影响各种神经递质胺的脑内水平来发挥作用。
