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维生素A中毒所致伴有可逆性门静脉高压的肝损伤：贮脂细胞的表现

Liver damage with reversible portal hypertension from vitamin A intoxication: demonstration of Ito cells.

作者信息

Guarascio P, Portmann B, Visco G, Williams R

出版信息

J Clin Pathol. 1983 Jul;36(7):769-71. doi: 10.1136/jcp.36.7.769.

DOI:10.1136/jcp.36.7.769
PMID:6863568
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC498385/
Abstract

A patient with sudden onset of ascites and hepatosplenomegaly made a complete recovery after vitamin A was withdrawn. Fluorescence microscopy on embedded tissue provided a simple method of demonstrating the accumulation of fat storage (Ito) cells in the liver.

摘要

一名突然出现腹水和肝脾肿大的患者在停用维生素A后完全康复。对包埋组织进行荧光显微镜检查提供了一种简单的方法来证明肝脏中脂肪储存（伊托）细胞的积聚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbe8/498385/9de7b8f77222/jclinpath00512-0048-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbe8/498385/2044c486ace3/jclinpath00512-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbe8/498385/9de7b8f77222/jclinpath00512-0048-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbe8/498385/2044c486ace3/jclinpath00512-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbe8/498385/9de7b8f77222/jclinpath00512-0048-b.jpg

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1
Liver damage with reversible portal hypertension from vitamin A intoxication: demonstration of Ito cells.维生素A中毒所致伴有可逆性门静脉高压的肝损伤：贮脂细胞的表现
J Clin Pathol. 1983 Jul;36(7):769-71. doi: 10.1136/jcp.36.7.769.
2
[Hepatic fibrosis and portal hypertension in chronic vitamin A poisoning].
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[Portal hypertension and hypervitaminosis A. Apropos of 2 cases and review of the literature].[门静脉高压与维生素A过多症。关于2例病例及文献复习]
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The hepatic stellate (Ito) cell: its role in human liver disease.肝星状（伊藤）细胞：其在人类肝脏疾病中的作用。

本文引用的文献

1
Paratentorial Grooving of Human Brains with Particular Reference to Transtentorial Herniation and the Pathogenesis of Secondary Brain-stem Hemorrhages.人脑幕旁沟回，特别涉及小脑幕切迹疝及继发性脑干出血的发病机制
Am J Pathol. 1968 Sep;53(3):391-408.
2
Hypervitaminosis A; report of a case in an adult.维生素A过多症；一例成人病例报告
J Am Med Assoc. 1951 Jun 30;146(9):788-93. doi: 10.1001/jama.1951.03670090020006.
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Vitamin A intoxication as a cause of pseudotumor cerebri.维生素A中毒作为假性脑瘤的一个病因
Virchows Arch. 1997 Mar;430(3):195-207. doi: 10.1007/BF01324802.
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Vitamin A intoxication presenting with ascites and a normal vitamin A level.维生素A中毒伴腹水且维生素A水平正常。
West J Med. 1988 Jan;148(1):88-90.
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Traditional management of liver disorders.肝脏疾病的传统管理方法。
Drugs. 1990;40 Suppl 3:45-57. doi: 10.2165/00003495-199000403-00005.
JAMA. 1960 Aug 20;173:1802-5. doi: 10.1001/jama.1960.03020340020005.
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HYPERVITAMINOSIS A: REPORT OF A CASE.
Am J Clin Nutr. 1965 Feb;16:265-9. doi: 10.1093/ajcn/16.2.265.
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CHRONIC HYPERVITAMINOSIS A. REPORT OF A CASE IN AN ADULT.
Arch Intern Med. 1963 Oct;112:462-6. doi: 10.1001/archinte.1963.03860040058003.
6
Chronic vitamin A intoxication; report of a case in an older child and review of the literature.慢性维生素A中毒；一名大龄儿童病例报告及文献综述
AMA J Dis Child. 1958 Jan;95(1, Part 1):57-68.
7
Hypervitaminosis A; report of a case in an adult.维生素A过多症；一例成人病例报告
J Am Med Assoc. 1956 Jul 21;161(12):1157-9. doi: 10.1001/jama.1956.62970120005010a.
8
Vitamin A poisoning in adults; with description of a case.成人维生素A中毒；附病例描述
Am J Med. 1954 May;16(5):729-45. doi: 10.1016/0002-9343(54)90281-8.
9
Hypervitaminosis A: report of a case in an adult male.维生素A过多症：一例成年男性病例报告。
Ann Intern Med. 1953 Jul;39(1):131-4. doi: 10.7326/0003-4819-39-1-131.
10
[Kupfer's cells and fat storing cells in the capillary wall of human liver].[人类肝脏毛细血管壁中的库普弗细胞和贮脂细胞]
Okajimas Folia Anat Jpn. 1952 Oct;24(4):243-58. doi: 10.2535/ofaj1936.24.4_243.