Mitchell A, Macey D J, Collin J
J Nucl Med. 1983 Jul;24(7):571-6.
The isolated in vivo intestinal segment is a popular experimental preparation for the investigation of intestinal function, but its value has been limited because no method has been available for measuring changes in intraluminal volume under experimental conditions. We report a scintigraphic technique for measuring intraluminal volume and assessing intestinal motility. Between 30 and 180 ml, the volume of a 75-cm segment of canine jejunum, perfused with Tc-99m-labeled tin colloid, was found to be proportional to the recorded count rate. This method has been used to monitor the effects of the hormone vasopressin on intestinal function.
离体肠段是研究肠道功能常用的实验标本,但由于在实验条件下尚无测量肠腔内容积变化的方法,其应用价值有限。我们报道了一种用于测量肠腔内容积和评估肠道蠕动的闪烁扫描技术。在用Tc-99m标记的锡胶体灌注的情况下,发现犬空肠75厘米肠段的容积在30至180毫升之间与记录的计数率成正比。该方法已用于监测血管加压素对肠道功能的影响。