Tuev A V, Nekrutenko L A
Kardiologiia. 1983 Apr;23(4):79-84.
Central and pulmonary circulation was studied in 111 patients with essential hypertension, stages I, IIa, IIb, using radio- and polycardiographic techniques. Pulmonary circulation changes associated with output hypertension were manifested in increased systolic pressure in the pulmonary artery and vascular volume of the lungs with increased venous return, and high blood flow rate combined with relatively normal pulmonary vascular resistance (total pulmonary resistance). Decreased cardiac output in vasoconstrictive pressor mechanism results from high total pulmonary resistance and reduced venous return, in addition to high peripheral resistance. Pulmonary hemodynamic changes were particularly pronounced in patients with normokinetic circulation. A quantitative assessment of relationships between major parameters of systemic and pulmonary circulation brought out close functional bonds within one circulatory variant. The findings obtained revealed similar patterns in the mechanisms of systemic and regional pressure formation in essential hypertension.
采用放射性和多心电图技术，对111例I期、IIa期、IIb期原发性高血压患者的体循环和肺循环进行了研究。与心输出量增加相关的肺循环变化表现为肺动脉收缩压升高、肺血管容量增加、静脉回流增加、血流速度加快，同时肺血管阻力（总肺阻力）相对正常。除了外周阻力升高外，血管收缩性升压机制导致的心输出量减少是由于总肺阻力升高和静脉回流减少所致。肺血流动力学变化在正常动力循环的患者中尤为明显。对体循环和肺循环主要参数之间关系的定量评估揭示了同一循环变体中的紧密功能联系。所获得的研究结果揭示了原发性高血压中体循环和局部压力形成机制的相似模式。
