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[以脑诱发性视觉障碍为亚急性硬化性全脑炎(SSPE)的首发症状]

[Cerebral-induced vision disorders as the initial symptom in subacute sclerosing panencephalitis (SSPE)].

作者信息

Lund O E, Förster C, Bise K

出版信息

Klin Monbl Augenheilkd. 1983 Apr;182(4):290-3. doi: 10.1055/s-2008-1054767.

Abstract

SSPE, the incidence of which is highest in children of school-age, is relatively frequently associated with bilateral acute central chorioretinitis (30%). Less common are initial visual disturbances in SSPE resulting from inflammatory processes of the encephalitis affecting cortical (occipital) areas and the visual pathways. We report on 2 cases detected after the patients had difficulty in reading and non-characteristic visual field defects. The diagnosis of panencephalitis may be confirmed by electrophoresis of spinal tap and of the EEG. The course of the disease is delayed and frequently lethal. Undefined, and at times seemingly psychogenic visual disturbances in children should always prompt immediate and intensive diagnostic efforts including pediatric and neurologic examination.

摘要

亚急性硬化性全脑炎(SSPE)在学龄儿童中发病率最高,相对频繁地与双侧急性中心性脉络膜视网膜炎相关(30%)。SSPE中由影响皮质(枕叶)区域和视觉通路的脑炎炎症过程导致的初始视觉障碍较少见。我们报告2例患者,他们在出现阅读困难和非典型视野缺损后被发现。全脑炎的诊断可通过脊髓穿刺电泳和脑电图来证实。该病病程迁延,常致命。儿童不明原因的、有时看似心因性的视觉障碍应始终促使立即进行深入的诊断工作,包括儿科和神经科检查。

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