Hammerstein W, Berger M, Hennekes R
Klin Monbl Augenheilkd. 1983 Apr;182(4):298-9. doi: 10.1055/s-2008-1054769.
The hemoglobin of 70 diabetics with retinopathy was analysed. 56 patients had pathologically elevated values, 12 values were within the upper normal limit and in 2 cases the findings were normal. This hemoglobin variant is characterized by an increased affinity of oxygen. Clinically and pathologically speaking the elevated HbA1c value could be a causal factor in diabetic retinopathy. Comparisons with sickle cell anemia and thalassemia seem to indicate that hemoglobinopathy and retinopathy are pathogenetically related.
对70例患有视网膜病变的糖尿病患者的血红蛋白进行了分析。56例患者的血红蛋白值在病理上升高，12例的值处于正常上限范围内，2例的检查结果正常。这种血红蛋白变体的特点是对氧气的亲和力增加。从临床和病理学角度来看，升高的糖化血红蛋白（HbA1c）值可能是糖尿病视网膜病变的一个致病因素。与镰状细胞贫血和地中海贫血的比较似乎表明血红蛋白病和视网膜病变在发病机制上相关。
