Brunner H, Schmut O, Faschinger C
Klin Monbl Augenheilkd. 1982 Nov;181(5):326-8. doi: 10.1055/s-2008-1055229.
HbA1 was determined in 12 juvenile diabetics with diabetic retinopathy and in ten adult diabetics at four-weekly intervals. During this time the course of the retinopathy was observed. Retinopathy was constant in juvenile diabetics with HbA1 values below 8%. A moderate progression, which it was possible to slow down by laser treatment, was observed in patients with HbA1 values of between 8% and 10%. Patients with HbA1 values exceeding 10% showed a marked progression, which could not be stopped by intensive laser therapy. The behavior of the retinopathy in adult diabetics corresponded to that of the juveniles when the onset of the disease was between the ages of 30 and 50. In elderly diabetics no significant tendency was observed.
对12名患有糖尿病性视网膜病变的青少年糖尿病患者和10名成年糖尿病患者每隔四周测定一次糖化血红蛋白（HbA1）。在此期间观察视网膜病变的进程。糖化血红蛋白值低于8%的青少年糖尿病患者的视网膜病变情况稳定。糖化血红蛋白值在8%至10%之间的患者观察到病情有中度进展，这种进展可以通过激光治疗减缓。糖化血红蛋白值超过10%的患者病情进展明显，强化激光治疗也无法阻止。当成年糖尿病患者在30至50岁之间发病时，其视网膜病变的表现与青少年患者一致。在老年糖尿病患者中未观察到明显趋势。
