van den Hove-Vandenbroucke M F, Couvreur M
Ann Endocrinol (Paris). 1978;39(2):137-8.
Sialic acid and iodine content were measured on 53 thyroglobulins from normal and pathological tissues. Sialic acid is significantly decreased in isolated cold nodules, and highly reduced in hot nodules and toxic adenomas. In these pathological situations, sialic acid defect could interfere with the iodination of the molecule.
对来自正常组织和病理组织的53种甲状腺球蛋白进行了唾液酸和碘含量的测定。在孤立性冷结节中,唾液酸显著减少,在热结节和毒性腺瘤中则高度降低。在这些病理情况下,唾液酸缺陷可能会干扰分子的碘化作用。