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[在早期筛选阶段鉴定抗生素物质的生物学方法]

[Biological method of identifying antibiotic substances at an early screening stage].

作者信息

Tikhonova A S, Chaĭkovskaia S M, Rezvan S P, Elizarova R N, Florova V I

出版信息

Antibiotiki. 1978 Aug;23(8):677-82.

PMID:686689
Abstract

A biological method was used in addition to the chemical methods of identification in the screening programme of new antibiotics. The method consists of evaluation of the effect of the crude antibiotic preparations on microbial forms resistant to various antibiotics. The efficiency of the biological method is shown. It provides more complete and rapid characterization of the properties of the new antibiotics and their rough identification at early screening stages.

摘要

在新抗生素筛选计划中,除了化学鉴定方法外,还采用了生物学方法。该方法包括评估粗制抗生素制剂对各种抗生素耐药微生物形态的影响。展示了生物学方法的有效性。它能在早期筛选阶段更全面、快速地表征新抗生素的特性并进行初步鉴定。

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