Mohs F E, Jones D L, Bloom R F
Arch Dermatol. 1978 Jul;114(7):1021-2.
Topical fluorouracil treatment of invasive basal cell carcinomas (BCC) is not recommended because it often produces the appearance of control with superficial inhibition of the tumor as the deeper extensions continue to grow, which results in a needless delay in obtaining effective treatment. These conclusions are based on data obtained during the microscopically controlled excision of 103 invasive BCCs of the face that had recurred after topical fluorouracil treatment.
不推荐使用局部氟尿嘧啶治疗浸润性基底细胞癌（BCC），因为它常常会造成肿瘤得到控制的假象，只是表面受到抑制，而深部浸润仍在继续生长，这就导致在获得有效治疗方面出现不必要的延误。这些结论是基于对103例面部浸润性BCC进行显微镜控制下切除时所获得的数据，这些病例在接受局部氟尿嘧啶治疗后出现了复发。
