Jamison T H, Cooper N M, Epstein W V
Arch Dermatol. 1978 Jul;114(7):1039-42.
A patient with the discoid lupus erythematosus and lichen planus overlap syndrome has profound depression of serum C4 concentration associated with substantial mixed cryoblobulinemia. A family study failed to disclose evidence of a familial hypocomplementemia, cryoglobulinemia, or a dermatologic condition. Immunologlobulin, but no complement, was detected at the site of the skin abnormality. This case illustrates an immune-complex disorder with a mixed cryoglobulinemia that is related to immunoglobulin deposition in the skin.
一名患有盘状红斑狼疮和扁平苔藓重叠综合征的患者血清C4浓度显著降低，并伴有大量混合性冷球蛋白血症。一项家族研究未发现家族性低补体血症、冷球蛋白血症或皮肤病的证据。在皮肤异常部位检测到免疫球蛋白，但未检测到补体。该病例说明了一种与混合性冷球蛋白血症相关的免疫复合物疾病，其与免疫球蛋白在皮肤中的沉积有关。
