Roujeau J C, Belghiti D, Hirbec G, Poli F, Sobel A T, Revuz J, Touraine R
Acta Derm Venereol. 1984;64(2):160-3.
A kidney biopsy was performed in 7 hypocomplementemic discoid lupus erythematosus patients despite the absence of overt renal involvement. Five patients had glomerular immune deposits and 2 patients with disseminated discoid lupus erythematosus exhibited definite proliferative glomerulonephritis. Those findings show that silent lupus nephritis may be encountered in discoid as well as in systemic lupus erythematosus, providing additional evidence supporting the unity of the disease. We suggest that hypocomplementemic patients with discoid lupus erythematosus must be carefully screened for renal disease by periodic urinalysis examinations.
尽管7例低补体血症性盘状红斑狼疮患者无明显肾脏受累表现，但仍对其进行了肾活检。5例患者有肾小球免疫沉积物，2例播散性盘状红斑狼疮患者表现为明确的增殖性肾小球肾炎。这些发现表明，盘状红斑狼疮和系统性红斑狼疮均可出现无症状性狼疮肾炎，为支持该病的统一性提供了额外证据。我们建议，对于低补体血症性盘状红斑狼疮患者，必须通过定期尿液分析检查仔细筛查肾脏疾病。
