Mantravadi R V, Spigos D G, Karesh S M, Pavel D G, Grady E G, Capek V
Radiology. 1983 Aug;148(2):555-9. doi: 10.1148/radiology.148.2.6867356.
Eight patients with locally extensive colorectal cancer were treated with colloidal P-32 chromic phosphate via the superior mesenteric artery following resection to prevent development of liver metastases. Less than 2% of the injected dose was found in the right atrial blood following the first pass through the liver and less than 1% in the urine. Therapy was tolerated well by all patients, with no acute complications. Long-term follow-up is needed to determine the effect of P-32 on the liver and the frequency of hepatic metastases.
8例局部广泛的结直肠癌患者在切除术后经肠系膜上动脉注入胶体磷酸铬P-32，以预防肝转移的发生。首次通过肝脏后，右心房血液中发现的注入剂量不到2%，尿液中不到1%。所有患者对该治疗耐受性良好，无急性并发症。需要长期随访以确定P-32对肝脏的影响以及肝转移的发生率。
