Kindley A D, Harris F
Arch Dis Child. 1978 Jul;53(7):590-2. doi: 10.1136/adc.53.7.590.
Meningitis may be difficult to diagnose. If it is suspected clinically and a first lumbar puncture is normal, a second cerebrospinal fluid (CSF) sample may be required within a few hours to confirm the diagnosis. A child is presented in whom CSF was normal 14 hours after the onset of illness, but who 14 hours later showed the characteristic changes of purulent meningitis. This case differs from those previously cited in the literature, in that the blood cultures taken at the time of the first lumbar puncture were also negative.
脑膜炎可能难以诊断。如果临床上怀疑患有脑膜炎，而首次腰椎穿刺结果正常，则可能需要在数小时内采集第二份脑脊液（CSF）样本以确诊。本文介绍了一名儿童，其发病14小时后的脑脊液检查结果正常，但14小时后却出现了化脓性脑膜炎的典型变化。该病例与文献中先前引用的病例不同，在于首次腰椎穿刺时采集的血培养结果也为阴性。
