de Montalembert M
Hôpital Necker-Enfants-Malades, Paris, France.
Pediatrie. 1993;48(1):17-9.
With few exceptions in extremely rare circumstances, such as sign of raised intracranial pressure, a lumbar puncture must be performed whenever the diagnosis of meningitis is suspected in a child. It serves to confirm a diagnosis of purulent meningitis, to identify the bacteria and to test its sensitivity to antibiotics. If the child responds appropriately to therapy, some authors recommend no further examination of cerebrospinal fluid (CSF). However, most prefer to control CSF sterilization after about 48 h of therapy. Apart from its bacteriological interest, this second lumbar puncture seems to be a prognostic indicator of the incidence of neurological abnormalities. No further CSF examination is necessary when the patient's course of illness is uncomplicated. On the other hand, the presence or appearance of neurological abnormalities during the daily physical and neurological examination compels a new lumbar puncture and a CT scan to search for a persistent central nervous system infection or a complication of the meningitis.
除了在极少数极端情况下,如颅内压升高的迹象外,只要怀疑儿童患有脑膜炎,就必须进行腰椎穿刺。它有助于确诊化脓性脑膜炎、识别细菌并检测其对抗生素的敏感性。如果患儿对治疗反应良好,一些作者建议不再进一步检查脑脊液(CSF)。然而,大多数人更倾向于在治疗约48小时后检查脑脊液是否无菌。除了其细菌学意义外,这第二次腰椎穿刺似乎是神经功能异常发生率的一个预后指标。当患者病程无并发症时,无需进一步检查脑脊液。另一方面,在每日体格检查和神经检查中出现神经功能异常或其表现,就需要再次进行腰椎穿刺和CT扫描,以寻找持续性中枢神经系统感染或脑膜炎并发症。