van Tongeren H A
Trans R Soc Trop Med Hyg. 1983;77(2):198-200. doi: 10.1016/0035-9203(83)90068-8.
A 29-year-old Dutch tourist of the Caucasian race had to break her return journey from Indonesia as she developed dengue haemorrhagic fever. She appeared to have been infected on Bali. Serological investigation revealed very high antibody titres against dengue virus types 1 and 3 and a moderately high titre against type 4 virus in the serum sample collected two weeks after onset of disease. In the sample taken 14 weeks after onset only more normalized antibody titres against type 1 and type 3 remained detectable. Although during earlier trips to the tropics she never showed signs of dengue fever, the timing of her first infection remains uncertain. The influence of age, race and double infections is discussed with relation to the cause of dengue haemorrhagic fever.
一名29岁的白种荷兰游客因患登革出血热，不得不中断从印度尼西亚返程的旅程。她似乎是在巴厘岛感染的。血清学调查显示，在发病两周后采集的血清样本中，针对1型和3型登革病毒的抗体滴度非常高，针对4型病毒的抗体滴度中等偏高。在发病14周后采集的样本中，仅能检测到针对1型和3型的抗体滴度恢复正常。尽管她此前前往热带地区旅行时从未出现过登革热症状，但她首次感染的时间仍不确定。文中讨论了年龄、种族和双重感染对登革出血热病因的影响。
