Aagaard J, Reuther K, Stimpel H
Urol Int. 1983;38(3):191-2. doi: 10.1159/000280889.
Emepronium bromide and flavoxate have both and separately been used with success in the treatment of detrusor instability. In this study we have combined the two drugs emepronium bromide and flavoxate and compared the results with emepronium bromide. 20 consecutive patients with an uninhibited bladder, 12 men and 8 women, were randomly allocated to treatment with either emepronium bromide/flavoxate or emepronium bromide. In this trial we found that treatment with the combination is significantly better than treatment with emepronium bromide only.
溴化依米普明和黄酮哌酯已分别成功用于治疗逼尿肌不稳定。在本研究中,我们将溴化依米普明和黄酮哌酯这两种药物联合使用,并将结果与溴化依米普明进行比较。20例连续性膀胱无抑制患者,男性12例,女性8例,被随机分配接受溴化依米普明/黄酮哌酯或溴化依米普明治疗。在该试验中,我们发现联合治疗明显优于单纯使用溴化依米普明治疗。