肾免疫母细胞肉瘤并发韦格纳肉芽肿病免疫抑制治疗

Renal immunoblastic sarcoma complicating immunosuppressive therapy for Wegener granulomatosis.

作者信息

Sant G R, Ucci A A, Meares E M

出版信息

Urology. 1983 Jun;21(6):632-4. doi: 10.1016/0090-4295(83)90212-1.

Abstract

A renal tumor developing in a patient receiving cyclophosphamide (Cytoxan) therapy for Wegener granulomatosis is reported. The tumor was similar histologically to the "immunoblastic" sarcoma that develops in renal allograft recipients as a complication of immunosuppressive therapy. This case report strengthens the cause and effect relationship between immunosuppressive drug usage and the subsequent development of neoplasia.

摘要

报告了一名在接受环磷酰胺（癌得星）治疗韦格纳肉芽肿病的患者中发生的肾肿瘤。该肿瘤在组织学上类似于肾移植受者作为免疫抑制治疗并发症而发生的“免疫母细胞性”肉瘤。本病例报告强化了免疫抑制药物使用与随后肿瘤形成之间的因果关系。