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重症肌无力患者的胸腺瘤

Thymomas in patients with myasthenia gravis.

作者信息

Slater G, Papatestas A E, Genkins G, Kornfeld P, Horowitz S H, Bender A

出版信息

Ann Surg. 1978 Aug;188(2):171-4. doi: 10.1097/00000658-197808000-00008.

Abstract

The records of 141 patients with myasthenia gravis who had thymomas were reviewed. In this series there were 69 noninvasive tumors and 52 invasive tumors. The five year survival for all patients was 60%, with the invasive group demonstrating a poorer prognosis than the noninvasive. The remission rates for the whole group (both invasive and noninvasive) of myasthenics was quite low (7%). Although the overall survival of this series of patients was relatively high, it is felt that by earlier diagnosis and a more aggressive surgical approach their prognosis will be even better.

摘要

对141例患有胸腺瘤的重症肌无力患者的记录进行了回顾。在这个系列中,有69例非侵袭性肿瘤和52例侵袭性肿瘤。所有患者的五年生存率为60%,侵袭性组的预后比非侵袭性组差。重症肌无力患者全组(侵袭性和非侵袭性)的缓解率相当低(7%)。尽管该系列患者的总体生存率相对较高,但认为通过早期诊断和更积极的手术方法,他们的预后会更好。

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本文引用的文献

1
Tumors of the thymus.胸腺肿瘤。
J Thorac Surg. 1950 Aug;20(2):195-215.
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Investigations into thymic disease and tumour formation.胸腺疾病与肿瘤形成的研究。
Br J Surg. 1955 Mar;42(175):449-62. doi: 10.1002/bjs.18004217502.
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The pathology of the thymus gland in myasthenia gravis.重症肌无力患者胸腺的病理学表现。
Ann N Y Acad Sci. 1966 Jan 26;135(1):496-505. doi: 10.1111/j.1749-6632.1966.tb45497.x.
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Surgery for thymic tumors.
Arch Surg. 1971 Jul;103(1):14-6. doi: 10.1001/archsurg.1971.01350070040008.
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