Ghezzi A, Caputo D, Zaffaroni M, Giussani D, Cazzullo C L
Acta Neurol Belg. 1983 Mar-Apr;83(2):80-7.
Electrophysiological tests (visual and somatosensory evoked potentials, flicker fusion test) and electrophoretic examination of cerebrospinal fluid were performed in 17 patients who previously suffered from one or more attacks of optic neuritis. The association of the tests revealed the demyelinating inflammatory pathogenesis in eight cases. In the remaining nine cases the CSF oligoclonal pattern was absent. The evidence that a bilateral delayed VEP, suggesting a subclinical contralateral involvement of optic pathways, could be related to multiple sclerosis, is discussed. A case was finally ascertained as being affected by Leber's optic atrophy.
对17例既往有一次或多次视神经炎发作的患者进行了电生理检查（视觉和体感诱发电位、闪光融合试验）及脑脊液电泳检查。检查结果显示，8例存在脱髓鞘炎性发病机制。其余9例脑脊液寡克隆带型阴性。文中讨论了双侧视觉诱发电位延迟提示视神经通路亚临床对侧受累可能与多发性硬化相关的证据。最终确诊1例为Leber视神经萎缩。
