Liedholm P, Srivastava K, Wingerup L, Astedt B
Acta Obstet Gynecol Scand. 1983;62(2):169-70. doi: 10.3109/00016348309155785.
From 18 apparently healthy women wearing a copper-IUD, endometrial biopsy specimens were obtained under hysteroscopic control, both from the site of the IUD and from a distant area. The fibrinolytic activity proved significantly higher in the former specimens than in the latter. The results provide a theoretical basis for the development of an IUD which releases a synthetic inhibitor of fibrinolysis.
从18名佩戴铜宫内节育器（IUD）的表面健康女性中，在宫腔镜控制下获取子宫内膜活检标本，标本取自IUD所在部位及远处区域。结果表明，前者标本中的纤溶活性显著高于后者。这些结果为开发一种释放纤溶合成抑制剂的宫内节育器提供了理论依据。
