Krone R J, Friedman E, Thanavaro S, Miller J P, Kleiger R E, Oliver G C
Am J Cardiol. 1983 Aug;52(3):234-9. doi: 10.1016/0002-9149(83)90114-5.
Follow-up results in 593 patients less than or equal to 7 years (mean 4.7) after hospital discharge for their first myocardial infarction (MI) are presented. Patients were grouped according to the presence or absence of Q waves on electrocardiograms after the MI and by peak serum glutamic oxalacetic transaminase (SGOT) level during hospitalization. Cardiac mortality varied. Patients with Q-wave infarcts and an SGOT level less than or equal to 240 IU/liter had a cardiac mortality of 3.1% per year, whereas patients with Q-wave MI and an SGOT level greater than 240 IU/liter had an 11% 6-month mortality and a 3.8% per year cardiac mortality thereafter. However, patients with non-Q-wave (nontransmural) MI had a excellent survival rate for 2 years (96.8%) which continued in patients aged less than or equal to 60 years thereafter. However, patients with non-Q-wave infarcts aged greater than 60 years had a 12% per year cardiac mortality in the third post-MI year and an additional 12% died each year thereafter. Early mortality was related to enzyme level, whereas late mortality was a function of type (Q-wave or non-Q-wave) and age.
本文呈现了593例首次心肌梗死(MI)出院后年龄小于或等于7岁(平均4.7岁)患者的随访结果。根据心肌梗死后心电图上Q波的有无以及住院期间血清谷草转氨酶(SGOT)峰值水平对患者进行分组。心脏死亡率各不相同。有Q波梗死且SGOT水平小于或等于240 IU/升的患者心脏死亡率为每年3.1%,而有Q波心肌梗死且SGOT水平大于240 IU/升的患者6个月死亡率为11%,此后心脏死亡率为每年3.8%。然而,非Q波(非透壁性)心肌梗死患者2年生存率极佳(96.8%),此后60岁及以下患者仍保持该生存率。然而,60岁以上非Q波梗死患者在心肌梗死后第3年心脏死亡率为每年12%,此后每年另有12%的患者死亡。早期死亡率与酶水平有关,而晚期死亡率则与梗死类型(Q波或非Q波)及年龄有关。