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首次Q波(透壁性)或非Q波(非透壁性)心肌梗死后的长期预后:593例患者分析

Long-term prognosis after first Q-wave (transmural) or non-Q-wave (nontransmural) myocardial infarction: analysis of 593 patients.

作者信息

Krone R J, Friedman E, Thanavaro S, Miller J P, Kleiger R E, Oliver G C

出版信息

Am J Cardiol. 1983 Aug;52(3):234-9. doi: 10.1016/0002-9149(83)90114-5.

DOI:10.1016/0002-9149(83)90114-5
PMID:6869266
Abstract

Follow-up results in 593 patients less than or equal to 7 years (mean 4.7) after hospital discharge for their first myocardial infarction (MI) are presented. Patients were grouped according to the presence or absence of Q waves on electrocardiograms after the MI and by peak serum glutamic oxalacetic transaminase (SGOT) level during hospitalization. Cardiac mortality varied. Patients with Q-wave infarcts and an SGOT level less than or equal to 240 IU/liter had a cardiac mortality of 3.1% per year, whereas patients with Q-wave MI and an SGOT level greater than 240 IU/liter had an 11% 6-month mortality and a 3.8% per year cardiac mortality thereafter. However, patients with non-Q-wave (nontransmural) MI had a excellent survival rate for 2 years (96.8%) which continued in patients aged less than or equal to 60 years thereafter. However, patients with non-Q-wave infarcts aged greater than 60 years had a 12% per year cardiac mortality in the third post-MI year and an additional 12% died each year thereafter. Early mortality was related to enzyme level, whereas late mortality was a function of type (Q-wave or non-Q-wave) and age.

摘要

本文呈现了593例首次心肌梗死(MI)出院后年龄小于或等于7岁(平均4.7岁)患者的随访结果。根据心肌梗死后心电图上Q波的有无以及住院期间血清谷草转氨酶(SGOT)峰值水平对患者进行分组。心脏死亡率各不相同。有Q波梗死且SGOT水平小于或等于240 IU/升的患者心脏死亡率为每年3.1%,而有Q波心肌梗死且SGOT水平大于240 IU/升的患者6个月死亡率为11%,此后心脏死亡率为每年3.8%。然而,非Q波(非透壁性)心肌梗死患者2年生存率极佳(96.8%),此后60岁及以下患者仍保持该生存率。然而,60岁以上非Q波梗死患者在心肌梗死后第3年心脏死亡率为每年12%,此后每年另有12%的患者死亡。早期死亡率与酶水平有关,而晚期死亡率则与梗死类型(Q波或非Q波)及年龄有关。

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引用本文的文献

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Ten year mortality in subsets of patients with an acute coronary syndrome.急性冠状动脉综合征患者亚组的十年死亡率。
Heart. 2001 Oct;86(4):391-6. doi: 10.1136/heart.86.4.391.
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Optimal therapeutic management of non-Q-wave myocardial infarction.非Q波心肌梗死的最佳治疗管理
Clin Cardiol. 2000 Jun;23(6):395-6. doi: 10.1002/clc.4960230602.
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Management of acute myocardial infarction in the elderly.老年人急性心肌梗死的管理
Drugs Aging. 1996 May;8(5):358-77. doi: 10.2165/00002512-199608050-00005.
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Prognostic significance of ST-T segment alterations in patients with non-Q wave myocardial infarction.非Q波心肌梗死患者ST-T段改变的预后意义
Heart. 1996 Jun;75(6):582-7. doi: 10.1136/hrt.75.6.582.
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Short and long term prognosis of acute myocardial infarction since introduction of thrombolysis.自溶栓治疗引入以来急性心肌梗死的短期和长期预后
BMJ. 1993 Aug 7;307(6900):349-53. doi: 10.1136/bmj.307.6900.349.
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First myocardial infarction in patients under 60 years old: the role of exercise tests and symptoms in deciding whom to catheterise.60岁以下患者的首次心肌梗死:运动试验和症状在决定哪些患者需要进行心导管插入术中的作用。
Br Heart J. 1993 Nov;70(5):428-32. doi: 10.1136/hrt.70.5.428.
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Residual myocardial jeopardy in patients with Q-wave and non-Q-wave infarctions.Q波和非Q波梗死患者的残余心肌危险
Br Heart J. 1987 Nov;58(5):460-4. doi: 10.1136/hrt.58.5.460.
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Br Heart J. 1989 May;61(5):396-402. doi: 10.1136/hrt.61.5.396.