Ramirez G, O'Neill W M, Lambert R, Bloomer H A
Arch Intern Med. 1978 Sep;138(9):1430-2.
Cholesterol embolization is not widely recognized as a complication of major arteriographic procedures. In a retrospective study of 71 autopsies of patients who underwent diagnostic arteriographic procedures (20 with aortograms, 51 with cardiac catheterization and coronary angiography), we found an incidence of cholesterol embolization of 30% and 25.5%, respectively, in comparison with 4.3% in an age and disease-matched control population. The organs most frequently affected are the kidney and spleen following aortogram, and the myocardium following cardiac catheterization. The clinical importance of these findings cannot be ascertained from this study, but our experience with a single case demonstrates that radiographic studies may produce substantial morbidity.
胆固醇栓塞并未被广泛认为是主要血管造影检查的并发症。在一项对71例接受诊断性血管造影检查患者的尸检回顾性研究中（20例行主动脉造影，51例行心导管检查和冠状动脉造影），我们发现胆固醇栓塞的发生率分别为30%和25.5%，而年龄和疾病匹配的对照人群中这一发生率为4.3%。主动脉造影后最常受累的器官是肾脏和脾脏，心导管检查后是心肌。这些发现的临床重要性无法从本研究中确定，但我们对一例病例的经验表明，影像学检查可能会导致严重的发病率。
