Hollis J H, Draper L R, Samson F
Am J Ment Defic. 1983 May;87(6):656-9.
Serum immunoglobulin levels for IgA, IgE, IgG, and IgM were measured in 13 institutionalized, profoundly mentally retarded individuals and for 20 retarded and 29 intellectually average noninstitutionalized individuals. A significant elevation in IgG was observed for the retarded groups as compared with the intellectually average group. There was a significant inverse relationship between IgG and level of intellectual functioning. The elevated IgG is suggestive of the findings with auto-immune diseases and warrants further investigation.
对13名机构收容的重度智力迟钝者、20名智力迟钝者以及29名智力正常的非机构收容者测量了血清中IgA、IgE、IgG和IgM的免疫球蛋白水平。与智力正常组相比,智力迟钝组的IgG水平显著升高。IgG与智力功能水平之间存在显著的负相关关系。IgG升高提示了自身免疫性疾病的相关发现,值得进一步研究。