Sassy-Dobray G, Kompolthy K, Winkler Z, Lukács J
Arch Geschwulstforsch. 1978;48(3):212-9.
The intraoperative cytological quick-examinations and quick-tests may influence way and type of the operation in cases of uncertain nature. They may lead to the fact that the original schedule of operation is kept to or changed. Thus, the operation is performed according to the situation, and lung tissue may be saved. Therefore, the possibility of a rapid diagnosis during the operation is of great importance. It is, however, often difficult or risky due to a potential tumour transplantation or due to other complications, to obtain respective tissue material for histological examination, above all, in such cases where the foci are located very deeply in the lung parenchyma. Therefore, the authors deal with the cytological examinations of 216 tissue samples taken from 187 patients intraoperatively (obtained by thoracotomy: 119 cases, by mediastinoscopy: 57 cases, by various surgical interventions: 20 cases). In 155 cases (82 per cent) the findings proved to be rightly positive or negative with regard to their malignity. The histological type diagnosis was correct in 79 per cent of all tumours. In 94 per cent of the nonmalignant processes the cytological finding was negative; besides, the authors point to the histological diagnosis of several types of benign tumours, Boeck-sarcoidoses, tuberculoses, other granulomatoses etc.
术中细胞学快速检查和快速检测可能会在病变性质不确定的情况下影响手术方式和类型。它们可能导致要么维持原手术计划,要么改变手术计划。因此,手术会根据具体情况进行,肺组织可能得以保留。所以,术中快速诊断的可能性至关重要。然而,由于存在潜在的肿瘤移植风险或其他并发症,要获取用于组织学检查的相应组织材料往往困难且有风险,尤其是在病灶位于肺实质深部的情况下。因此,作者对187例患者术中采集的216份组织样本进行了细胞学检查(通过开胸手术获取:119例,通过纵隔镜检查获取:57例,通过各种手术干预获取:20例)。在155例(82%)病例中,关于恶性与否的检查结果被证明正确为阳性或阴性。所有肿瘤中79%的组织学类型诊断正确。在94%的非恶性病变中,细胞学检查结果为阴性;此外,作者还指出了几种良性肿瘤、结节病、结核病、其他肉芽肿病等的组织学诊断。